Methotrexate is a tablets. Methotrexate is most often "heard about" as
an anti-cancer (anti-neoplastic) drug, and it is an "antimetabolite"
but is specific to interrupting the synthesis phase in a cell’s cycle.
Actually, it binds to an enzyme needed to manufacture "purine," which
is one of the base groups used for forming DNA and RNA. Since the
purine building block is locked out, the cell cannot manufacture a
complete set of nucleic acids. Therefore the cell cannot proceed to
the final growth phase and progress to mitosis (cell division) — such
a cell will have no progeny and its own life span will soon become
crippled with old age since it wont be able to "repair itself."
This is the logic and expected performance range for methotrexate, so
its application goes beyond treating only cancerous tissues. Other
conditions where there is unwanted cellular proliferation can benefit

from treatment with this extremely powerful drug.
Under the big tent of eczema, psoriasis (severe) can often be tamed
with small doses of methotrexate. And, also pertaining to the skin, it
can be used effectively to treat very advanced (and recalcitrant)
mycosis fungoides.
It is also sometimes very effective in treating rheumatoid arthritis
if it is both severe and refractory (nonresponsive to other, kinder
treatments). It’s in this context that I often have to work with the
drug. Some patients do remarkably well with the medication; others do
not. Because of its manner of action, the drug is indirectly
immunosuppressive.

So far, I am not sure what is happening but I’m still itching and
getting fructration. And also we are in Winter season and my skin is
getting too dry. I spoken to my doctor and said that it will take
quite a while to react. So i have to wait and see. If it doesn’t work
then I will stop. BUt first see what happen. Hold thumbs for me!

Glenda

Terri

Glenda

Glenda